The Journal of Leukocyte Biology is a monthly peer-reviewed medical journal covering all aspects of immunology.

The journal is published by the Society for Leukocyte Biology.

It was originally published by Academic Press.

In 1984 the Reticuloendothelial Society changed its name to the Society for Leukocyte Biology and the journal obtained its current name.

Rebuck, Quenten Myrvik (1974–1980), and Carleton Stewart (1981–1994).