He is the uncle of Juan García Ábrego, his successor in the cartel and once considered Mexico's most-wanted man.

Through shrewd political connections he had fostered, Nepomuceno Guerra was able to control all the contraband moving across the Rio Grande.

[3] In the 1970s, his nephew Juan García Abrego began utilizing those connections and developed the organization into a drug cartel primarily dedicated to the more lucrative business of smuggling cocaine.

[4] According to news sources, despite allegedly founding one of the largest drug cartels in Mexico, Juan Nepomuceno Guerra never spent more than "a few hours in jail" for his crimes.

[6][7] In Narcos: Mexico, Juan Nepomuceno Guerra is played by the Mexican actor Jesus Ochoa.