Juan Pérez de la Serna (1570 – 8 August 1631) was a Spanish Catholic prelate who served as Archbishop of Zamora (1627–1631) and as the seventh Archbishop of Mexico (1613–1627).

[1][2][3][4] Juan Pérez de la Serna was born in Cervera del Llano, Spain.

[2][3] On 13 May 1613 he was appointed by the King of Spain and confirmed by Pope Paul V as the seventh Archbishop of Mexico.

[1][2] On 19 July 1627 he was appointed by Pope Urban VIII as Archbishop (personal title) of the Diocese of Zamora, Spain where he served until his death on 8 August 1631.

[1][2] He died in Zamora, Spain.