Born in Zapotiltic, Santiago began playing football with the youth side of Atlas before making his senior debut in 1999.
In a more than 10-year career, Santiago played for Atlas, Veracruz, Santos Laguna and Tijuana.
[1] The central defender won the Primera División with Santos in 2008.
[2] On 9 March 2013, he announced his retirement from professional football.
This biographical article related to a Mexican association football defender is a stub.