He was born at Medina de Pomar in the Province of Burgos (rather than Alcalá, as some writers state).
Alvarez Gomez and Andrea Schott state that Medina was buried in the church of St. Ildefonsus.
The Council of Trent declares that at the hour of death there is no "reservatio" and that all priests can absolve "in articulo mortis".
His opinions on the "materia" for sacramental absolution, and on the "Copia confessariorum" seem opposed to the teaching of the council on these points.
His brother John de Medina brought out the theological books at Alcala in 1544 and sqq.