[1] Juan del Pozo Horta was born in Valladolid and ordained a priest in the Order of Preachers.
[2][3] On 16 July 1646, he was appointed during the papacy of Pope Innocent X as Bishop of Lugo.
[1][2][3] On 14 October 1646, he was consecrated bishop by Giulio Rospigliosi, Titular Archbishop of Tarsus, with Miguel Avellán, Titular Bishop of Siriensis, and Timoteo Pérez Vargas, Titular Bishop of Lystra, serving as co-consecrators.
[2][3] On 10 January 1650, he was appointed during the papacy of Pope Innocent X as Bishop of León.
[1][2][3] On 1 April 1656, he was selected by the King of Spain and confirmed by Pope Alexander VII on 28 August 1656 as Bishop of Segovia.