[1] The team's name was chosen to honor statesman Benito Juárez, who described himself as the son of Indians of the primitive race of the country.

[2] Organized Mexican baseball started in 1937, when a league featuring teams from the cities of México, Tampico and Veracruz played a modest 25 game schedule.

Gradually increasing the number of games, the independent Mexican baseball circuit was playing nearly a 100-game schedule by the end of World War II.

The league included six franchises that represented Mexico City (Aztecas), Chihuahua (Dorados), El Paso (Tejanos), Saltillo (Peroneros), Torreón–Gómez Palacio (Laguneros), and Ciudad Juárez (Indios).

As a result, the MNL México and Torreón clubs retired in late April and the remaining of the league collapsed on May 27, just when Juárez and Chihuahua were tied in first place with a 23-21 record.

In 1947 the Indios de Ciudad Juárez took refuge in the Class C Arizona–Texas League, but suspended operations during the midseason and were replaced by the Mesa Orphans.

[11] The Indios were successfully in this three-year span, claiming their second championship title in 1952 with an 84-55 record, and ending 74-65 for a third place in 1953.

Then, the league expanded from six to eight teams in 1954 and became more competitive, which affected the Indios performance, which ended last with a 55-85 mark, 38 games out first place.

[8] The Indios found itself on the move again, this time in the short-lived Mexican Center League, a Class C six-team circuit that operated from 1956 to 1957.