The largest localities (cities, towns, and villages) are:[1] Juchitepec (Xochiltepetl) was founded in 1381 by a ruler named Acamapixtli.

Juchitepec was one of the first places conquered by the Spanish because it was on the route Hernán Cortés took when he arrived.

On July 3, 1531, a decree was written which defined Juchitepec's eight districts: Cuautzozongo, Calayuco, Zancalco, Oacalco, Tetlancheo, Tepepatlacher, Tlacotlapilco and Tlacaelcalpam.

The Mexican Revolution impacted Juchitepec because in 1911 some of the first Zapatista groups entered and demanded money from the rich.

The typical food of Juchitepec is mole, barbecue, chicken or calf mixiote and carnitas prepared in a special way, popcorn, cheese tamales, rajas and corn and bean tlacoyos.