In 1152, the Aztecs, on their way from Tula-Xicocotitlan to Tequixquiac and the Valley of Mexico, decided to settle for a short time at a place called Tepetongo.

At this time the Viceroy Luís de Velasco made regulations on the Encomienda system, mandating the protection of indigenous people.

By 1552, families dispersed by a Tlaxcaltec named Francisco Lopez de Tlaltzintlale were gathered and stripped of their land; these possessions were distributed through royal grants to Spaniards, some was Marranos or New Christians (Sephardic settlement converted to Roman Catholic religion).

With the help of the Franciscan friars, the temple of Saint James the Apostle was built, raising Tequixquiac from the rank of vicarage to parish.

[further explanation needed] There is an open chapel with columns on the facade and two stone jambs built by Native Americans and carved with work from their philosophical perspective.

At the beginning of the political jurisdiction,[clarification needed] Tequixquiac covered the current territory of Tlapanaloya without the people to be integrated into the eighteenth century.

'Mexican nation adopts for its government as representative of People's Federal Republic,' published in the same way the oath to the Constitution of the United Mexican States in October 1824.

[incomprehensible][citation needed] The Grand Canal was built through Tequixquiac during the presidency of Porfirio Díaz in order the drain the Valley of Mexico.

It was the second phase of construction by British company Mexican Prospecting and Finance Co Ltd. y la Read & Campbell in 1867,[3] the workers stayed in encampments around the Hacienda of Acatlan in El Tajo de Tequixquiac.

The first mayor denounced by citizens in high federal courts, upon proving acts of corruption and embezzlement of money, was Salvador Raúl Vásquez Valencia and some members of his city council.

[1] The highest mountain in Tequixquiac is the Cerro Mesa Ahumada, with an elevation of 2,600 metres (8,500 ft) above sea level,[8] on the border between the municipalities of Huehuetoca and Apaxco.

[9] Plants native to the municipality include: Native animals include: cacomistle, skunk, gopher, Virginia opossum, rabbit, Mexican gray squirrel, turkey, colibri, turkey vulture, northern mockingbird, rattlesnake, pine snake, xincoyote (Sceloporus spinosus), red warbler, rufous-crowned sparrow, lesser roadrunner, great horned owl, axolotl, frog, toad, red ant, bee, and others.

The tunnel has been a locus of infection and waste gases given off by sewage from residential, commercial, industrial, and hospital areas of Mexico City.

Tequixquiac Tunnel causes debate among the locals, the Comición Nacional del Agua (National Water Commission), and different levels of government.

During the Spanish conquest and colonial period, this road was used for merchant traffic including freight of stone, silver, gold, lime, fruits, corn, wood, wine and furnitures.

The Spanish built the camino real (English: royal road) from Tepotzotlán to Actopan, connecting with Camino Real de Tierra Adentro, crossing by Coyotepec, Huehuetoca, Tequixquiac, Tlapanaloya, Hueypoxtla, Apaxco, Santa Maria Ajoloapan, Ajacuba, Tezontlale, Ixcuincuilapilco, San Agustín, Tecama, Tepenene and Chicabasco.

The principal destinations are Indios Verdes, Martín Carrera and Cuatro Caminos subway stations in Mexico City, for public transport to Hueypoxtla, Zumpango and Apaxco.

[15] Tequixquiac has produced calcium oxide since the time of the Aztec Empire when Otomi people paid tribute in Hueypoxtla province.

[16] During the 19th century Tequixquiac was also recognized for corn agriculture and pulque production inside their haciendas; this beverage was transported to Mexico City on donkeys or mules.

The municipality's economy has traditionally been based in agriculture, especially in the growing of corn, alfalfa, tomato, wheat, chili and bean, mostly used for auto-consumption.

[clarification needed] However, climatic change has diminished harvests and the growth of commerce in the form of small and medium-sized businesses has grown.

Industry here is minimal, consisting of agro-industry in milk and forage; Tequixquiac produces cheese, cream, butter, tostadas and handcraft beer.

The second-largest religious community is that of Jehovah's Witnesses who have a Kingdom Hall located in the suburb of San Mateo and acceptance this denomination has spread rapidly throughout the town.

In the 19th and 20th centuries important engineering works include the El Tajo channel, Calcium Horns and Chimney, Vicente Guerrero school, Methodist church, Municipal Hall, Cuatro Caminos bridge, old cemetery, Casa de los Párrocos, La Cinco channel, and the Portales and Main Plaza.

The wind band Longinos Franco, a native of the Barrio El Refugio, is a guardian and interpreter of the contradanza de Las Varas, and dissemination of music under the guidance note wind symphony, paso doble, marches, a large repertoire of Mexican folk music and modern popular music.[24][relevant?]

A musical group Los Bybys, which originated in Tequixquiac in 1991, has appeared in many cities and toured the United States, Argentina, Paraguay, Peru and Bolivia.

The hills of Tequixquiac had been used to pasture cows and rams, and the Spanish had very large haciendas and found it necessary to employ indigenous people as vaqueros or herdsman, who soon became excellent horsemen.

In Barrio de San Mateo, there is evidence that previously played in front wall of the engineers who built Tequixquiac Tunnel and ports, this area is called the pediment precisely.

Another legacy of the engineers is the practice of baseball by elderly adults as Arnaldo Paez Navarro and 74-year-old Don Felix Vasquez Flores.

Today baseball is played at Deportivo El Salado, site near to La Cinco and other sports such as association football and basketball.