In the main event, World Champion Rey Mysterio defeated John "Bradshaw" Layfield (JBL) following a Frog splash.

Judgment Day was first held by World Wrestling Entertainment (WWE) as the 25th In Your House pay-per-view (PPV) in October 1998.

[4] The main feud heading into Judgment Day 2006 involved Rey Mysterio and John "Bradshaw" Layfield (JBL) with the two battling over the World Championship.

On the May 5 episode of SmackDown!, after Mysterio expressed his feelings about being World Champion, JBL came out and declared himself the number-one contender.

[5][6] The next week on SmackDown!, JBL announced that Mysterio would take on The Great Khali later that night.

[7][8] On the May 19 episode of SmackDown!, JBL said that Mysterio did not look so well due to the beatings he endured in past weeks and that he probably did not even know what day it was.

[9] The other main match on the card was Booker T versus Bobby Lashley in the finals of the 2006 King of the Ring tournament.

[10] He announced the participants and that the first match, Kurt Angle versus Randy Orton, would take place next week.

[7][8] Angle was unable to compete due to the injuries to his ribs that he sustained after being attacked by Henry.

[5][6] Before the event went live on pay-per-view, Matt Hardy defeated Simon Dean in a dark match.

[1][4] After a largely back and forth match, Mercury accidentally ran into Nitro, who hit Melina on the outside.

[1][4] Benoit took advantage after three German suplexes, but missed a diving headbutt, allowing Finlay to gain control.

[4] After some more back and forth offense, Sharmell caused another distraction, allowing Booker's associate Finlay to hit Lashley with a shillelagh.

[1][4][21] Khali dominated the match for large periods, although the Undertaker did manage to execute his signature Old School.

[4][23] In the main event, Rey Mysterio defended the World Championship against John "Bradshaw" Layfield (JBL).

[4][25][24] JBL then brought a steel chair into the ring, but Mysterio dropkicked it back into his face.

[27] King Booker also continued his feud with Bobby Lashley,[27][28][29] until they finally had their blow-off match inside a steel cage.

[30] King Booker went on to become the number one contender to the World Championship,[31] while Finlay and Regal continued the Court's feud with Lashley.

[27] Angle went on to wrestle the returning Randy Orton at ECW One Night Stand, after storyline breaking his ankle in April.

[30] The Undertaker accepted the match the following week, sending a message over the speakers, and interrupting a segment where Daivari and Khali were mocking him.

[31] The Undertaker made his first appearance on SmackDown!, since Judgment Day, the following week to send a message to Khali.

[35] Before the match at the Great American Bash, however, Khali was replaced with the Big Show,[36] due to a problem with his liver.