She was an intern and resident at Beth Israel Deaconess Medical Center and an endocrinology fellow at Yale School of Medicine.

"[1] A major component of Fradkin’s leadership tenure at NIDDK is the Special Statutory Funding Program for Type 1 Diabetes Research.

She also treated people who sought care at the Walter Reed National Military Medical Center endocrinology clinic.

Her leadership and oversight of research dedicated to the prevention, treatment, and cure of diabetes, and other metabolic and endocrine disorders, improved healthcare for millions of Americans.

Around NIDDK, Fradkin was known for her attention to detail, ability to think quickly on her feet, broad knowledge, precision in communication, as well as her compassion, collegiality, wit, and generosity.