He is best known for being a member of the British vocal group Blake and his portrayal of Harry Tressler in the medical drama Holby City.

[9][10] In January 2013, Knight was told that he had won the part of Harry Tressler in Holby City after doing four auditions over two and a half months.

[14] In June 2016, Knight was cast in the recurring role of Spencer Koenigsberg, Queen Helena's new Lord Chamberlain, on The Royals.

[15] In February 2015, it was announced that Knight had decided to relaunch his music career, with a solo album after previously having been in a band.

[13] Discussing his new career path, he stated: "In many ways making a solo album is a totally natural progression for me and has been a long time coming."

Speaking about the album, he said: "The connection between them is that they're all poignant, emotive songs that have affected me in some way in my life, and will hopefully strike a chord with people of all ages.