[2] Born in Porto Alegre, Rio Grande do Sul, she is best known for her role as Letícia Gomes da Silva, the main character of the 2004 season of the telenovela Malhação.

[3] Her career as an actress started when she played the role of the preteen character Mariana in the short movie Fora de Controle.

[5] Juliana Didone has also acted in several television commercials of various companies, like Grendene,[4] Halls,[4] Guaraná Antarctica,[4] and Shiseido, of Japan.

[9] She signed a contract with Rede Record in 2013 and she was part of the cast of the first telenovela by the author Carlos Lombardi in that network, Pecado Mortal.

In March 2006, Juliana Didone and her partner, Leandro Azevedo, won the Brazilian version of the TV reality show Dancing with the Stars, called Dança dos Famosos.