She is best known to western audiences for her appearances in the Quentin Tarantino films Kill Bill: Volume 1 and Inglourious Basterds, in which she played Sofie Fatale and Francesca Mondino respectively.

[2] After finishing the course, she moved to Tokyo working part-time in a design studio while continuing her private Japanese lessons.

Centering on a mystery drama, chief producer Motoyoshi Sei hired Dreyfus to increase ratings by changing the program into an episode format.

[3] Eventually, she was cast by Japanese network executives as the twenty-something beauty in several TV and film roles, leading her to become a gaijin tarento (foreign talent).

[4][5] Dreyfus appeared in Vinyan in 2008 and in Tarantino's war epic Inglourious Basterds in 2009, as Francesca Mondino, a fictional French interpreter and mistress for Nazi propagandist Joseph Goebbels.