[8] Kedzie rose to prominence in mixed martial arts on November 19, 2005, when she won the one-night HOOKnSHOOT Women's Grand Prix in Evansville, Indiana.
On February 10, 2007, Kedzie faced undefeated rising star Gina Carano in a featured bout at EliteXC: Destiny, which aired live on Showtime.
[15] Kedzie's fight with Sarah D'Alelio was then rebooked for Jackson's MMA Series 3 on December 18, 2010 in Albuquerque, New Mexico.
[18] Kedzie defeated Young by unanimous decision to become Jackson's MMA Series Women's Bantamweight Champion.
[19] Kedzie was scheduled to fight Amanda Nunes at the Strikeforce: Overeem vs. Werdum event on June 18, 2011, in Dallas, Texas.
[24] Kedzie was expected to face Germaine de Randamie as part of the Strikeforce Challengers 19 card on September 23, 2011, but withdrew due to injury.
[32] She lost the fight via split decision and subsequently announced her retirement from mixed martial arts competition via Twitter.