She was named chamber maid to queen Marie Leczinska and succeeded her aunt Marie Marguerite Bibault as Première femme de Chambre in 1765.
After the queen's death in 1768, she was transferred to the household of Marie Antoinette in 1770.
Marie Antoinette called her as l'impératrice reine ('Empress Queen').
[1] She was pointed out as a political intriguer at court, and claimed to be an ally of Paul François de Quelen de la Vauguyon and an agent of the Jesuits and the Devots.
In 1775, the office of Première femme de Chambre was split in four, between de Misery and her three deputies Henriette Campan, Marie-Élisabeth Thibault and Quelpée La Borde Regnier de Jarjayes, who took turns serving: they were all still in service when the queen's household was dissolved in 1792, at that time in supervision of six chamber maids (femme du chambre).