[6] Going through the years, Vermote had results on all levels and his time trialling skills started to develop with multiple wins in the discipline.

He took his first victory with the team in March 2012, when he took the general classification at the Driedaagse van West-Vlaanderen after teammate Michał Kwiatkowski withdrew from the race on the final day.

[14] At the 2014 Tour of Britain, Vermote won the seventh stage of the race, having made a solo attack from a five-rider breakaway group with around 17 kilometres (11 miles) remaining.

[15] A week later, Vermote won a bronze medal at the UCI Road World Championships, as part of the Omega Pharma–Quick-Step squad riding in the team time trial.

Vermote had been a part of the breakaway, which was later joined by a group of overall contenders on the hilly route, before he was the only other rider to follow an attack by Steve Cummings on the run-in to Kendal.

[2] Over the next two seasons, Vermote recorded three top-ten individual placings; finishing ninth at Kuurne–Brussels–Kuurne – being part of a breakaway that was caught with 100 metres (330 feet) remaining[22] – and eighth at the Grand Prix d'Isbergues in 2018, and tenth at Paris–Tours in 2019.

[23] He then joined Cofidis for the 2020 season (who were returning to the top level of cycling as a UCI WorldTeam),[24] where he worked largely as a domestique during the COVID-19 pandemic-effected campaign.