He was named to the team for the 2022 Tour de France and ended up playing an important role.

Between Roglič, Jonas Vingegaard and Wout van Aert fighting for stage wins, jerseys and the Tour de France itself, Van Hooydonck was one of the key domestiques for the team.

[6] He is the son of former professional cyclist Gino and the nephew of two-time Tour of Flanders winner Edwig Van Hooydonck.

On 12 September 2023, he suffered an initially undescribed medical issue causing him to be involved in a traffic incident.

Jonas Vingegaard won the stage of the Vuelta a España that was held that day and dedicated his win to Van Hooydonck.