James Roday, Dulé Hill, Timothy Omundson, Maggie Lawson, Corbin Bernsen, and Kirsten Nelson all reprised their roles as the main characters in the series.

[4] The previously announced musical episode, originally thought to be part of the sixth season, aired during the seventh as a two-hour event in December 2013.

Corbin Bernsen continued as Henry Spencer, and Kirsten Nelson returns as SBPD Chief Karen Vick.

Kurt Fuller and Sage Brocklebank reprised their recurring roles as Woody the Coroner and Officer Buzz McNab, respectively.

[10] Parminder Nagra appeared in a recurring role as Rachael, a beautiful and charming woman for whom Gus falls; she is later revealed to be a single mother.

Other guest stars for the season included Rose Abdoo, Garcelle Beauvais, Rachel Blanchard, Barry Bostwick, Cocoa Brown, Cindy Busby, Jake Busey, Tate Ellington, Pete Gardner, Lauriane Gilliéron, Neil Grayston, Gregory Harrison, David Koechner, Christopher Lloyd, Lori Loughlin, Brooke Lyons, Jessica Makinson, Eddie Matos, Mike McGlone, Katy Mixon, Rebeka Montoya, Garrett Morris, Oliver Muirhead, Martin Mull, Josh Pais, Tony Plana, Kirsten Prout, Anthony Rapp, Kate Rogal, Ethan Sandler, Big Show, Joey Slotnick, Sebastian Spence, Mike Starr, Steve Valentine and Lesley Ann Warren.