Born in Asunción, Paraguay, Granada moved to the United States with her mother at the age of 14 in 2001 after receiving a scholarship to attend the David Leadbetter Golf Academy in Bradenton, Florida.

Granada turned professional in June 2005 at age 18 and competed on the Futures Tour that summer, joining in mid-season.

[1] She placed second in her first and sixth events and won her first professional title at the season-ending YWCA Futures Classic in late August in York, Pennsylvania.

[2] Granada won $29,153 in nine Futures Tour events to finish seventh on the 2005 money list,[3] which advanced her to the final stage of the LPGA qualifying tournament in December.

She won the final round of the elimination-format event in Florida to claim the first $1 million prize in women's golf and vaulted up to fourth on the money list.