[4] A multidisciplinary visual artist, Manna works in multiple mediums, including installation art and film.
[12] Manna's work explores the effects of preservation practices in the fields of agriculture, science and law.
[13][14] Manna's 2015 film A Magical Substance Flows Into Me focuses on Robert Lachmann's quest to create an archive of "oriental music" in Jerusalem.
[5] In 2017, Manna released her second film Wild Relatives, which focused on the Svalbard Global Seed Vault in Norway and its relationship with the International Center for Agricultural Research in the Dry Areas (ICARDA) and ICARDA's stored seeds from the Lebanon’s Bekaa Valley amidst the backdrop of the Syrian Revolution.
[16][17] From September 2022 to August 2023, Manna had her first major American museum exhibition titled "Break, Take, Erase, Tally," at MoMA PS1.