Born in Lagodekhi, Kakheti (eastern Georgia), he graduated from Tbilisi Agricultural Institute.
By isolating opposition groups, Patiashvili forced reformist leaders into underground organizations and confrontational behavior.
Following the tragedy, the Georgian national liberation movement radicalized and left little chance to a local communist leadership to control the situation in the Republic.
He organized an oppositional Unity (ertoba in Georgian) party joining the oppositional bloc united behind the Democratic Revival Party led by Aslan Abashidze, regional leader of Adjara, and was elected in the Parliament of Georgia.
He ran in the 2008 Georgian parliamentary election from the Gori constituency on the Rightist Alliance–Topadze-Industrialists bloc ticket.