She married broadcaster Angelo Castro Jr. in 1973 and the couple had three children: Diego, an actor and anchor of UNTV,[3] Gabriella, and Angelica.
She appeared in several films, including Durog (1971), and Lunes, Martes, Miyerkules, Huwebes, Biyernes, Sabado, Linggo (1976).
[4] During the People Power Revolution in late February 1986, Keithley continued her broadcasts at the radio station booth of DZRJ-AM in Santa Mesa, Manila where she, along with Father James Reuter, Felino Interia, and Charlie Frejas, set up Radyo Bandido, which was an alternative source for news on the uprising after government troops destroyed the transmitter of Church-owned Radio Veritas on 23 February.
As soldiers failed to discover their whereabouts despite proximity to Malacañang Palace, Radyo Bandido helped sustain momentum for the revolt that ultimately toppled the dictatorship of President Ferdinand Marcos on 25 February.
[11] Keithley was portrayed by Odette Khan in the 1988 Australian television film A Dangerous Life, in a scene depicting her role in Radyo Bandido during the People Power Revolution.