St. Paul University Manila (SPUM), also referred by its acronym SPU Manila, is a private, Catholic coeducational basic and higher education institution established and run by the Congregation of the Sisters of Saint Paul of Chartres in Manila, Philippines.

[2] In 1912, St. Paul Manila opened a Kindergarten school with an enrollment of six girls, upon request of the families in the neighborhood.The school was named St. Paul Institution.

It is one of the 40 schools owned, managed, and operated by the Sisters of St. Paul of Chartres (SPC) in the Philippines.

It is one of the seven campuses comprising the St. Paul University System.

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