He established his own trading house and had close ties to the state, both under the reign of Christian VI and Frederik V. He participated with great success in the expeditions to China and India which were planned and supported by Bernstorff on behalf of the state.
He took part in the preparations for the expedition led by Verrayon to the Levant with the aim of opening a new, lucrative market.
In 1745, he took part in Johan Frederik Classen's development of an establishment of a cannon and munitions factory at Frederiksværk, contributing mainly with contacts and funding.
One of their daughters, Charlotte Fabritius, married Peter van Hemert.
Another daughter, Anna Susanne Fabritius (1737–1792), married Johann Schultze.