He is best known for playing Rafael Solano on the CW telenovela Jane the Virgin (2014–2019) and for starring in and directing the romantic drama film It Ends with Us (2024).

Its contentious filming received substantial media coverage, as both Lively and Baldoni filed lawsuits related to the production.

[3] In December 2024, Lively filed a lawsuit against Baldoni and his production company Wayfarer Studios, accusing them of sexual harassment and intimidation.

In 2008, Baldoni wrote, produced, and directed his first music video that was selected and won him his first "Audience Choice Award" at Dawn Breakers International Film Festival.

[18] From 2014 to 2019, Baldoni played Rafael Solano in the CW satirical telenovela Jane the Virgin starring opposite Gina Rodriguez.

Baldoni directed and produced CBS Films' Five Feet Apart, starring Cole Sprouse and Haley Lu Richardson, and based on an original script by Mikki Daughtry and Tobias Iaconis.

[30] Pulitzer Prize award-winning journalists Megan Twohey and Mike McIntire from The New York Times investigated the allegations and reported that Baldoni had hired a PR crisis firm in order to "bury her" through a coordinated smear campaign against her across social media platforms such as TikTok, Reddit, and X.

[31] Baldoni responded with a $250 million defamation lawsuit against the newspaper, saying that the article's authors had pulled quotes so far out of context as to be the opposite of the truth.

[37] Plank left the podcast in 2024 after The New York Times reported allegations that Baldoni sexually harassed Blake Lively.

[56][57] Baldoni is on the Board of Ambassadors of the Tahirih Justice Center, a nonprofit advocating for women, girls, and all immigrant survivors of gender-based violence.

[58] On December 20, 2024, actress Blake Lively filed a complaint with the California Civil Rights Department against Baldoni for sexual harassment and retaliation on the set of It Ends with Us (2024).

[31] Baldoni has denied the accusations, and his lawyer, Bryan Freedman, produced a statement describing Lively's claims as "completely false, outrageous and intentionally salacious.

[68][69] Baldoni's lawyer stated, "In this vicious smear campaign fully orchestrated by Blake Lively and her team, the New York Times cowered to the wants and whims of two powerful ‘untouchable’ Hollywood elites, disregarding journalistic practices and ethics once befitting of the revered publication by using doctored and manipulated texts and intentionally omitting texts which dispute their chosen PR narrative.

It was based on a review of thousands of pages of original documents, including the text messages and emails that we quote accurately and at length in the article.

The lawsuit named Baldoni; his film studio, Wayfarer; and the two public relations representatives, Melissa Nathan and Jennifer Abel.

[71] On 16 January 2025, Baldoni's attorney filed a $400 million lawsuit against Blake Lively, her husband Ryan Reynolds, and their publicist Leslie Sloan for civil extortion, defamation, and invasion of privacy.

[63] On January 31, Baldoni filed a 168-page timeline of events, including text messages, to support the assertion that Lively had conducted a smear campaign against him.

[73][74] Baldoni contends that Lively, along with Reynolds and Sloan, engaged in a coordinated effort to tarnish his reputation, derail his career, and obscure the film’s original purpose of highlighting domestic violence awareness.