As a freshman at George Washington University he made 28 appearances and was 10–2 with one save and a 1.68 ERA, ranking second in the Atlantic 10 Conference.

He transferred to Virginia Commonwealth University for his sophomore season and won Baseball America second team All-American honors and All-Colonial Athletic Association accolades.

[3] Orenduff was selected by the Los Angeles Dodgers in the 1st round of the 2004 MLB Draft and assigned to rookie-class Ogden Raptors for the conclusion of the season.

Orenduff struggled at AAA Las Vegas at the start of the 2007 season and returned to Jacksonville, where his numbers improved.

Orenduff was designated for assignment and removed from the 40 man roster on March 8, 2009, to make room for Manny Ramirez.