Although she started her career in Malayalam cinema with the song "Valakilukkam Kettedee" from the film Pranayamani Thooval in 2002.

Some of her hits are "Karuppinazhagu" from Swapnakoodu, "Melleyonnu" from Manassinakkare, and "Meheruba" from Perumazhakkalamand also Raftara in "Lucifer" in Malayalam Some of her latest films are Classmates, Pothen Vava, Don, Notebook and Janmam.

She has traveled to the UK, the US, Australia and Singapore for musical programs, and has performed with almost all leading playback singers of south India.

She concluded another North American tour with singer G. Venugopal and in August 2013 in Australia with Unni Menon performing for Malayalees in major cities.

On 26 December 2010, Jyotsna married Sreekanth Surendran, a software engineer from Kochi.