This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
[1] Ketamine is an NMDA receptor antagonist, developed in the 1960s to induce anesthesia in patients but recreational users have found great appeal in its antidepressant, dissociative and hallucinatory effects that are characteristic of the k-hole experience.
During k-hole, users experience an enhanced detachment from the environment, resulting in an inability to respond to surroundings and move their bodies functionally.
[4] Physical health problems, like the so-called "K-cramps" and gastric pain, and unappealing mental side-effects, like "memory loss" and "decreased sociability" are also reported post-k-hole.
[6] About half of the recreational users describe the k-hole as a positive experience, as it provides "a short escape from their daily problems".