[2] The Malankara Mar Thoma Syrian Church ordained Mathew as a clergyman in 1955 and he became a vicar in Mylom.

In 1981, Mathew was made Principal of the Mar Thoma Theological Seminary and continued in that position till 1986.

Mathew was also on the panel of Professors under the Federated Faculty for Research in Religion and Culture[8] (FFRRC), Kerala and served as a guide to post-graduate and doctoral students.

In 2000, he was invited by the Mar Thoma Syrian Church of Malabar (Delhi Diocese) to serve as the Principal[9] of Dharma Jyoti Vidyapeeth {affiliated to the Senate of Serampore College (University)}, Faridabad.

He left the college again in 1968 to spend a year at the University of Hamburg, Germany under Klaus Koch.

After leaving the Seminary in Kottayam in 1994, Mathew spent three years as a Vicar of the Parish in Ranni.