The station airs local sports-talk and carries nationally syndicated Fox Sports Radio programming.

Programming on KKBQ and KKBQ-FM ("93Q") simulcasted until January 16, 1998, when the AM station became the adult standards-formatted "Star 790 KBME" (for "Best Music Ever", although a joke among employees was "Keep Bringing Me Ex-Lax").

At that point, KBME's sports talk programming shifted to a mix of local shows and programs from Fox Sports Radio, including the launch in late 2009 of "Matt & Adam in the Morning," a morning show hosted by Matt Jackson and Adam Wexler, who both moved over from KILT.

Previous hosts on KBME include Brad Davies, Carl Dukes, Ted Deluca, John Lopez, David Dalati, Tom Franklin.

The Sports Animal simulcasted their aftermath coverage as a public service to those who may have evacuated to the Houston area, and continued to do so until November 2005.

Beginning with the 2012-2013 season, KBME became flagship station to the NBA's Houston Rockets, with iHeartMedia (then known as Clear Channel Communications) acquiring the team's radio rights from CBS Radio-owned KILT.