It is owned by the Salem Media Group with studios and offices on North King Street in Honolulu's Kalihi district.

KGU-FM is a brokered programming station where hosts pay for their time on the air and may use their shows to seek donations to their ministries.

National religious leaders heard on KGU-FM include David Jeremiah, Jim Daly, Charles Stanley, J. Vernon McGee and Chuck Swindoll.

In 2003, KHUI became the first station in the United States to play a Variety Hits format when it brought Bob FM to the Honolulu radio market.

On December 26, 2010, KHUI flipped from Adult Standards to a simulcast of Salem's Christian Talk sister station KGU 760 AM.