Gene tissue expression patterns found through the National Center for Biotechnology Information UniGene EST Profile showed that there was also high expression of RESF1 in the lymph nodes, uterus, mouth, thyroid, larynx and blood.
[10] An evaluation of RESF1 expression in health states was performed using NCBI Unigene’s EST Profile.
However, RESF1 may be related to adrenal tumors, as there was lower expression of this gene within normal kidney tissue.
EXOC1 functions as a response to microbial infections, which reduces viral RNA synthesis and protein translation.
This study used affinity purification combined with high accuracy mass spectrometry to find specific protein interactions.
[22] MDM2 is a gene that interacts with others to affect the cell cycle and apoptosis, and is located in tissues common to RESF1, such as the uterus and lymph node.
[26] The closest orthologs to RESF1 are primates, however, conserved sequences can be found in whales, bears, snakes, birds, turtles, and frogs.