Along with WIL-FM, KMOX is responsible for the activation of the Greater St. Louis Emergency Alert System for hazardous weather, disaster declarations, etc.,[citation needed] and is the EAS primary entry point for eastern Missouri and southern Illinois.

KMOX airs a talk radio format with blocks of news every morning and in weekday afternoon drive time.

Three nationally syndicated shows run overnight, Our American Stories with Lee Habeeb, The Other Side of Midnight with Frank Morano and America in the Morning with John Trout.

On weekend mornings, all-news blocks start the schedule, followed by programs on money, health, car repair, home improvement and old time radio dramas and comedies.

KMOX has a large team of local newscasters and reporters, and airs updates from CBS News Radio at the beginning of most hours.

KMOX also has an agreement to share news gathering and weather information with KMOV, the CBS television network affiliate for St. Louis.

[8] In addition, stations were informed that if they wanted to continue operating, they needed to file a formal license application by January 15, 1928, as the first step in determining whether they met the new "public interest, convenience, or necessity" standard.

[9] On May 25, 1928, the FRC issued General Order 32, which notified 164 stations, including KFQA, also in St. Louis, that "From an examination of your application for future license it does not find that public interest, convenience, or necessity would be served by granting it.

The FRC initially disapproved of this proposal, and ordered KFQA deleted,[11] but eventually relented, and assigned KMOX to be operated under the dual call sign of KMOX-KFQA.

[12] On November 11, 1928, the FRC made a major reallocation of station transmitting frequencies, as part of a reorganization resulting from its implementation of General Order 40.

In the early days of radio, KMOX broadcasts had been picked up in Scotland, New Zealand, the Arctic Circle and South Africa.

[15][16] In 1933, KMOX covered the first post-Prohibition shipment of Budweiser beer leaving the Anheuser-Busch St. Louis brewery for the White House, a story carried nationally by CBS.

[citation needed] Through the "Golden Age of Radio," KMOX carried the CBS schedule of dramas, comedies, news, sports, soap operas, game shows and big band broadcasts.

[17] On March 29, 1941, KMOX moved from 1090 to 1120 kHz, as part of the implementation of the North American Regional Broadcasting Agreement (NARBA).

Because of an FCC regulation in place then that prohibited TV and radio stations in the same market, but with different ownership, from sharing the same call sign, Channel 4 changed to KMOV.

By the late 1960s, KMOX-FM was separately programmed, airing an easy listening format, then later shifted to Top 40 as KHTR in 1982, and is currently classic hits KLOU, owned by iHeartMedia, Inc.

In July 1968, CBS opened a new studio and office facility in downtown St. Louis to house KMOX-AM-FM-TV, which until that point had been operating from separate locations.

As network programming shifted from radio to television in the 1950s, KMOX switched to a full service format of talk shows, news, and middle of the road (later adult contemporary) music.

It was Hyland who leveraged KMOX's relationship with the St. Louis Cardinals, signing many lucrative advertising contracts with local businesses.

That program, like the sports and talk shows that soon followed, pioneered a format for radio featuring news maker interviews, guest appearances, and calls from listeners.

Following Rush Limbaugh's death, the station launched a new, local show hosted by longtime news reporter Carol Daniel in its midday timeslot.

Bob Costas did play-by-play on KMOX for the Spirits of St. Louis of the American Basketball Association from 1974 until the ABA-NBA merger in June 1976.

[32] KMOX aired University of Missouri Tigers football and basketball games for many years, and was the flagship of their radio network until the 1990s.

[34] Notable current and past KMOX broadcasters include: ** = Audacy operates pursuant to a local marketing agreement with Martz Communications Group.