KNPG-CD (channel 21) is a low-power, Class A television station in St. Joseph, Missouri, United States, affiliated with NBC, The CW Plus and Telemundo.

The station's history traces back to the September 21, 1998, launch of a cable-only affiliate of The WB that was originally managed and promoted by St. Joseph Cablevision (a cable television provider that was owned by the News-Press & Gazette Company), alongside the launch of The WB 100+ Station Group, a service similar to The CW Plus that was created to expand national coverage of The WB via primarily local origination channels managed by cable providers in markets ranked above #100 by Nielsen Media Research.

Since it was a cable-exclusive outlet that was not licensed by the Federal Communications Commission, the channel used the callsign "WBJO" in a fictional manner.

Before the sign-on of the cable-only WBJO, viewers in the St. Joseph area received their WB network programs via Superstation WGN, and in September 1996, KCWB when the station began broadcasting, then from KSMO-TV when that station dropped UPN and picked up the WB from KCWB, in which it changed the call letters to KCWE two years later.

[citation needed] KNPG-LD displaced KSHB-TV (channel 41) – which is among the seven full-power Kansas City stations that provide city-grade signal coverage in St. Joseph proper – as the area's default NBC station on Suddenlink Communications, DirecTV and Dish Network.

However, after News-Press and Gazette relaunched channel 21 as NBC affiliate KNPG-LD on November 1, 2016, KNPN began providing simulcasts of local news programs originating on that station as well as additional newscasts produced exclusively for KNPG, using the former's existing news department staff.

On that date, it began simulcasting the first 90 minutes of KNPN's weekday morning newscast (which runs on that station for 2+1⁄2 hours, with the remaining hour airing exclusively on channel 26 as KNPG airs Today during the 7 a.m. hour of the broadcast) and its half-hour 5 p.m. newscast (the weekend editions of which moved to KNPG following the switch, due partly to frequent preemptions on channel 26 caused by predetermined or gameplay-caused overruns by Fox Sports event broadcasts).