Prominent persons who have been regulars on KPFT include science educator David F. Duncan and humorist John Henry Faulk.

[2] Beginning in the mid-1970s, KPFT began airing multiple shows for the local LGBT audience, including Wilde 'n' Stein (1975-early 1990s) and After Hours (1987-early 2000s).

[5] In July 2021, Pacifica and KPFT management chose to sell the station's Montrose-area premises at 419 Lovett Blvd., citing "prohibitive" repair costs to the building.

Five months later, October 6, 1970, while the station was broadcasting Arlo Guthrie's "Alice's Restaurant," the transmitter was bombed yet again and the damage was significantly more extensive.

[10] On January 21, 1971, KPFT management invited Guthrie to visit the Houston studios, where he performed "Alice's Restaurant" live as the station commenced transmitting yet again.

After months of inactivity by the Federal Bureau of Investigation and local police, Pacifica took the initiative to mount a media campaign designed to draw attention to the unsolved case and seek support for pressuring authorities to act.

Federal agents ultimately arrested a member of the Ku Klux Klan, Jimmy Dale Hutto,[11] and charged him with the KPFT bombings, as well as with plotting to blow up radio stations KPFA and KPFK.

[12] Raj Mankad wrote at OffCite that the KPFT bombings in 1971 were part of a larger campaign of "threats and acts of violence against progressive and radical institutions in Houston," including underground newspaper Space City!

[13] In the early morning hours of August 13, 2007, a bullet was fired into the studio, breaking a window and narrowly missing a woman's head, but no one was injured.