The motorcycle is one of the most successful machines of the Moto3 era to date, having taken five constructors' championships, including a clean sweep in 2013 winning every one of the 17 races.

The elliptical shaped air intake is placed on the front fairing, while the duct that connects it to the airbox passes under the steering head.

The RC250R features a number of differences compared to the RC250GP,[2][4] including For the Red Bull MotoGP Rookies Cup, KTM prepares identical, sealed motorcycles for each rider.

As a marketing move by KTM to promote its new brand, Husqvarna entered the Moto3 paddock as a unique manufacturer in the 2014 and 2015 seasons with its FR250GP motorcycle.

[8] Similar to the previous move with Husqvarna, KTM entered GasGas as a unique manufacturer in the Moto3 championship starting from 2021 with Aspar Team.

[9] KTM's Chinese partner CFMoto entered the Moto3 championship as a unique manufacturer with Prüstel GP starting from 2022, using rebranded RC250GP bikes.