For a brief period, KQOK also aired reruns of the classic western series Bonanza and national newscasts produced by the Independent News Network.

On May 27 of that year, Equity sold KQOK to Oklahoma City-based Tyler Media Group, becoming the company's first television station property.

To accommodate the station's plans to launch local programming catering to Oklahoma's Latino community, Tyler Media expanded the company's existing Shields Boulevard facility, constructing two production studios for use for KTUZ's news and public affairs programming, and a third, larger studio for varied usage, including possible use for town hall events.

The deal, which was approved by the FCC on July 1, placed KUOK in the unique position of being the junior partner in a duopoly with a Telemundo-affiliated station, a rarity given that Univision is the longer established and, on a national level, higher rated of the two networks.

It also airs a local sports show on Saturday nights (similar in format to Telemundo's Ritmo Deportivo) called Fiesta Deportiva, airing immediately following Telemundo's national sports program Titulares Telemundo at 10:30 p.m. From the 2005 affiliation switch until September 2007, the station also aired Studio Z (produced in conjunction with KTUZ-FM), a weekly music video program hosted by KTUZ-FM personality Blanca Estela Ramirez, showcasing videos from Latin music artists.

After switching to Telemundo, KTUZ had no full-fledged newscasts other than two-minute daily news and weather updates that were produced out of a small studio which aired during the network's daytime and primetime programs.

In August 2013, Tyler Media appointed Martin Bedoya as news director for the program, who intended to improve the quality of Acción Oklahoma's content as well as the station's newsroom operations.

(KTUZ assumed the full-power affiliation rights to QVC and HSN from Ion affiliate KOPX-TV [channel 62], which had displaced them in favor of Defy TV and TrueReal on their respective 62.5 and 62.6 subchannels on June 30, the day prior to the latter two Scripps-owned networks' formal launches, temporarily leaving QVC and HSN without full-market over-the-air availability in the Oklahoma City DMA—beyond low-power affiliations—until the addition of the KTUZ subchannels.)