The station is owned and operated by the Ion Media subsidiary of the E. W. Scripps Company.
The call letters became KWPX-TV on March 9, 1998, after the station was purchased by Paxson Communications, replacing ValueVision with its inTV network until the launch of Pax on August 31, 1998.
Until 2021, the station carried Telemundo on its seventh subchannel, before Scripps' purchase of Ion Media nullified the agreement, in order to carry their own subchannel networks.
Cox-owned KIRO-TV relaunched the network in the market in the fall of 2022 over subchannel 7.4.
The station's signal is multiplexed: KWPX-TV shut down its analog signal, over UHF channel 33, on February 17, 2009, to conclude the federally mandated transition from analog to digital television.