[8][9] Her daughter, Waneek Horn-Miller (born 1975), was stabbed in the chest by a soldier's bayonet while holding her younger sister, Kaniehtiio, then aged 4; a photograph of the incident, published on the front page of newspapers, symbolized the standoff between Mohawks and the Canadian government.

In the 1960s and early 1970s, Kahn-Tineta Horn became widely known for her criticisms of anti-native racism and government policy regarding First Nations peoples, and for her advocacy of native separatism.

"[14] By 1972, her separatist views had appeared in the pages of The Harvard Crimson and The New Yorker,[15][16][17] and she had been interviewed by The Webster Reports of KVOS-TV, a Bellingham, Washington station which broadcasts to Vancouver, British Columbia.

[18] Kahn-Tineta Horn has appeared in two short films, Artisans de notre histoire, Volume 2: Les Explorateurs (1995) and David Thompson: The Great Mapmaker (1964).

[22] In 2006, Kahn-Tineta Horn was one of two women who submitted a "notice of seizure" to the developers of the Melancthon Wind Farm near Shelburne, Ontario on behalf of the Haudenosaunee,[23] and taught a history class at Concordia University in Montreal.