Starnes became involved in the martial arts at an early age and began teaching when he was a teenager.

And has also practiced Muay Thai, Boxing, Judo, Aikido, Kung Fu, Taekwondo, Greco Roman Wrestling, Shotokan and Wado Ryu Karate.

Starnes made his UFC debut on June 24, 2006 at the finale of The Ultimate Fighter 3, winning via rear naked choke over Danny Abbadi.

After this Starnes would gain the biggest victory in his career, by defeating Chris Leben on May 26, 2007 at UFC 71 via unanimous decision, also winning the Fight of The Night bonus for his efforts.

Starnes was criticized by MMA pundits and fans for avoiding Quarry for the majority of the match, leading to a new nickname, "The Running Man."