One of the largest domed structures in the world, it features a naturally-ventilated design with a retractable roof, and has configurations for football, rugby, athletics and cricket.

Due to Singapore's tropical climate, the stadium's roof is designed to reflect sunlight in order to insulate its interior, while natural airflow is used to cool spectator areas with less energy usage than a venue of comparable size.

[16] Singapore Sports Hub CEO Oon Jin Teik stated that the stadium's unique microclimate had posed additional challenges in maintaining the GrassMaster pitch.

[19] The stadium also held the edition of a friendly tournament, the 2017 International Champions Cup which features three major European clubs: Chelsea, Bayern Munich and Inter Milan.

The following year, it hosted the 2018 International Champions Cup which also features three big clubs from Europe: Arsenal, Atletico Madrid and Paris Saint-Germain.

The 2019 International Champions Cup saw four major European clubs participating in the tournament: Juventus, Tottenham Hotspur, Manchester United and Inter Milan.

Cristiano Ronaldo, widely regarded as one of the greatest football players of all time, also played at the stadium scoring a goal against Tottenham.

On 15 July 2022, the stadium hosted the Standard Chartered Singapore Trophy, a preseason friendly between Premier League clubs Liverpool and Crystal Palace.

[24] AS Roma were later replaced by Lion City Sailors of the Singapore Premier League, after the club was forced to pull out of the match after a pair of friendlies in South Korea were cancelled due to financial issues with their promoter.

[87] Under the contract between the Sports Hub and Singapore Government, NDP organisers were allowed 45 days of free annual usage of the venue.

Contrarily, it was argued that not hosting the NDP at the new National Stadium would free up its schedule for major international sporting events, especially during the summer months.

[90][91] Bids to host the Asia Masters Athletics Championships and the Merlion Cup at the stadium had also previously been stalled by costs demanded by the facility.