She is primarily recognized as the eldest offspring of Ieyasu, notable for her active participation in the Siege of Nagashino and her significant role in the events leading to the downfall of Honda Masazumi.

Kamehime was the eldest daughter of Matsudaira Motoyasu, who later became famous as Tokugawa Ieyasu, and his formal wife, Lady Tsukiyama.

This endeavor led to the proposal of Kamehime's marriage to Okudaira Nobumasa, the lord of Shinshiro Castle, as part of a larger alliance orchestrated by Oda Nobunaga.

[5] Kamehime helped her husband and send Torii Suneemon on the mission to cross the enemy army to request aid to her father, Ieyasu in Okazaki and defended the Nagashino castle.

[6] Kamehime's father intentions in the Battle of Sekigahara were shaped by his desire to consolidate power, secure his position in a fractured Japan, and lay the foundation for the Tokugawa shogunate.

Kamehime harbored ill feelings towards Masazumi due to his involvement in the demotion of Ōkubo Tadachika, a hereditary daimyō, who had close ties to the Okudaira clan.

During a visit by Tokugawa Hidetada, her younger brother from a different mother and the second shōgun of the Edo bakufu, to Nikkō to pay homage at a shrine, he stayed in Utsunomiya Castle.

Since April 2008, Kamehime has been characterized as a navigator for a municipal administration program produced in Shinshiro City, Aichi Prefecture.