Kami-Kuwanagawa Station (上桑名川駅, Kami-Kuwanagawa-eki) is a railway station in the city of Iiyama, Nagano Prefecture, Japan operated by the East Japan Railway Company (JR East).

Kami-Kuwanagawa Station is served by trains on the Iiyama Line, and is 35.4 kilometers from the starting point of the line at Toyono Station.

[1] The station consists of one side platform serving one bi-directional track built on an embankment.

[1] Kami Kuwanagawa Station opened on 16 September 1931.

With the privatization of Japanese National Railways (JNR) on 1 April 1987, the station came under the control of JR East.