[3] The previous clubs Glik played for include Piast Gliwice from 2008 to 2010, Palermo from 2010 to 2011, Torino from 2011 to 2016 and Monaco from 2017 to 2020, the latter two of which he was appointed captain of the team.

[7] Glik began his career in the youth ranks of MOSiR Jastrzębie Zdrój and WSP Wodzisław Śląski, then moved on loan to LKS Silesia Lubomia.

In 2006, he moved from WSP Wodzisław Śląski to Horadada in Spain, where he was noticed by Real Madrid and registered with the club's "C" team.

At the end of the season it was reported that he had begun talks with Italian side U.S. Città di Palermo;[10][11] on 7 July 2010, he signed with Sicilian club, who purchased him outright on a five-year contract.

He made his debut with the Rosaneri in the 2010–11 UEFA Europa League play-off round against Slovenia's Maribor (won 3–0), played as a starter.

A few days before the official reopening of the transfer market, Palermo granted an exemption and allowed him to train – with a recovery date set for 28 December – with his new team, Bari.

He scored his first goal in the 34th round, in the match Torino - Reggina, later suspended due to bad weather[18] (the conclusion of the game did not change the result).

[23] On 31 July 2014, he made his debut with the Granata in international competition, playing the first leg of the third qualifying round of the UEFA Europa League, won 3–0 against the Swedes Brommapojkarna.

[30] In an official statement on the Torino website, the club stated "It has been five wonderful years, intense, full of emotions and mutual satisfaction.

"[31] On 27 September 2016, Glik fired in a half-volley from the edge of the penalty box four minutes into second-half stoppage time to cancel out Javier Hernández's goal, enabling Monaco to snatch a 1–1 home draw in their 2016–17 UEFA Champions League Group E encounter against Bayer Leverkusen with their first and only shot on target of the match.

[32] Glik played a main part in the Monaco side, which won the 2016–17 Ligue 1 title making 36 appearances and scoring 6 goals.

[33] On 11 August 2020, newly promoted Serie A club Benevento announced the signing of Glik from Monaco on a three-year contract.

[43] Glik is a tall centre back with great physicality, but also good mobility;[44][45] his biggest strength is undoubtedly his aerial ability, both in marking and on set pieces in the opposing area.