It travels south through the Clock Tower neighborhood and on through Kibuye, Kajjansi, and Abayita Ababiri before ending at the airport, a distance of about 40 kilometres (25 mi).

Kampala–Entebbe Road accommodates an estimated 264,000 passengers every day, as of May 2016.

[3] Other credible sources quoted traffic on this road at 635,656 vehicles annually, in 2011.

[4] Before the opening of the Entebbe–Kampala Expressway, this road was the only direct link between the city center and the international airport.

[5][6] Because of the congestion, the road is one of the most automobile accident-prone locations in the country.