He was the younger brother of Kanō Tan'yū, with whom he completed a number of prominent commissions for the Tokugawa shogunate.
His style differed somewhat from Tan'yū's in his bold use of negative space and his mastery of ink wash painting.
[1] Naonobu's skills differed somewhat from Tan'yū's, particularly taking after his mentor Kanō Kō-i and delving into ink wash painting and his bold use of negative space.
On gilt sliding doors and partitions he tended to suggest the form of the subject rather than delineate it.
[1] Works such as the Fujimi saigyō-zu byōbu screen show his interest in contrasts, depicted an enormous, barely-delineated Mount Fuji against a background of mostly negative space with a tiny seated figure gazing up at it.