The typical format of the show was for the hosting duo to interview a panel of celebrity guests on various topics while engaging in comedic banter.
The show had originally been named "Qi Guai Shi Dian Zhong" (奇怪十點鐘, "Weird 10 o'clock"), but was changed to Kangsi Coming soon after its debut.
Kangsi was noted for its interest in celebrity gossip and embrace of subcultures, with a fast-paced, tongue-in-cheek, and fully self-aware style, even when approaching occasionally controversial or serious topics.
The show also incorporated cartoon sound effects, comical editing techniques like instant replays, and wacky animated texts and visuals.
Politicians Andy Lau, Eason Chan, Edison Chen, Carina Lau, Ng Man Tat, Eric Tsang, Nicholas Tse, Shawn Yue, Wong Jing, Cecilia Cheung, Stephen Chow, Twins (band), Joey Yung, Lydia Shum, Vivian Chow, Fiona Sit, Ronald Cheng, Josie Ho, Anita Yuen, Wakin Chau, Joyce Cheng, Anthony Wong, John Woo, Jacky Cheung, Jaycee Chan, Timmy Hung, Kelly Chen, Grasshopper (band) Huang Lei, Huang Xiaoming, Tao Hong, Qin Hailu, Hai Qing, Huang Haibo, Zhao Wei, Yang Zishan, Huang Bo, Liu Liyang, Huang Yali, Jing Boran, Yu Kewei, Ding Ding, Zhang Hexuan, Zhang Wei, Li Jianjun, Anson Hu, Li Bingbing, Zhang Hanyu, Xiao Shenyang, Hu Xia, Ding Dang, Liu Yan, Huang Shengyi, The New Seven Little Fortunes, Ye Zixuan, Yang Qingqian, Jason Zhang, Xie Na, Lu Yao, Best Crew, Na Ying, Chen Kaige, Chen Hong, Chen Jianbin, Han Geng, Yan Yidan, Guo Jingming, Yu Quan, Zheng Kai, TFBoys, Wang Yibo, Li Wenhan, Zhou Yixuan, Wang Xiaofei, Fan Bingbing, Li Chen Seth Rogen, Michel Gondry (The Green Hornet), Wonder Girls, Stefanie Sun, Kris Phillips, Take That (Band), Coco Lee, Henry Lee, JJ Lin, Maria Ozawa, Atsushi Tamura, By2, Gary Chaw, Ah Niu, A-do, Michael & Victor, Penny Tai, Eric Moo, Jet Li, Bai Ling