Kara-Bom is an Initial Upper Paleolithic archaeological site dating to 46,620 +/-1,750 cal years before present (BP), and located in Southern Siberia.

It is among the earliest (probable) modern human sites for Siberia, together with Kara-Tenesh, Kandabaevo, and Podzvonskaya.

[2] The site of Kara-Bom has lithic assemblages consisting in classic and elongated Levallois points.

The site would represent a key station in the expansion of modern humans associated with the IUP wave out of Southwest Asia slightly before 47 ka cal BP, one of the next stations being Ust-Ishim.

They ended in Bacho Kiro cave and Oase, but this wave of colonization did not go as far as Western Europe, and apparently was not successful.