[3] She began training in ballet at the age of three in Chapel Hill, commuting from her family's home in Durham.
Medoff earned a full Trinity Scholarship to attend Duke University, where she studied pre-medicine and dance and volunteered with the student-run Emergency Medical Services group.
[7][8] Medoff began working at the Lincoln Center for the Performing Arts during her last year at Harvard Business School through the HBS Leadership Fellows program, a program dedicated to connect graduating MBA students with nonprofit and public-sector arts organizations.
In 2015, Medoff lead the launch of the Lincoln Center Global Exchange, a gathering of international leaders of various industries focused on exploring what roles art and culture play in facing critical challenges across the globe.
[10] Medoff was a founding producer and board member of Ars Nova, an Off-Broadway theatre production company based in Hell's Kitchen, Manhattan.
[2] She served on the advisory committee of the American Theatre Wing, which created and produces the Tony Awards.